8%) patients sustained head injuries. Of these, 41 (54.0%) sustained mild head injury, 20 (26.3%) patients sustained moderate head injury and 15 (19.7%) www.selleckchem.com/products/BafilomycinA1.html patients had severe head injury. The majority of patients, 398 (88.1%) had systolic blood pressure (SBP) > 90 mmHg on admission and the remaining 54 (11.9%) patients had SBP of 90 mmHg and below. Admission CDK inhibitors in clinical trials patterns and treatment
Most of patients (296, 65.5%) reported within 24 hours after injury. The time interval between injury and arrival to the A & E department ranged from 2 hours to 5 days with a median of 22 hours. The waiting time, defined as the time interval taken from reception at the A & E department and reception of treatment ranged from GS-7977 clinical trial 30 minutes to 10 hours with a median of 3.00 hours. The majority of patients, 302
(66.8%) were attended to within 6 hours of arrival to the A & E department. Most of animal related injuries, 312 (69.0%) were so mild that after conservative (non-surgical) treatment (such as wound dressing, antibiotics, analgesics, tetanus toxoid, antirabies etc) at the A & E department the patients were discharged home. Only 140 (31.0%) patients were hospitalized. Of these, 102 (72.9%) were admitted to the surgical wards and the remaining 38 (27.1%) were admitted to the intensive care unit (ICU). All patients were administered antibiotics of varying nature at the A and E department. Analgesics (parenterally or orally) were also given to all patients. Four hundred and forty (97.3%) patients received tetanus toxoid and ninety-six (21.2%) patients received antirabies. Blood transfusion was given to twenty-one (4.6%) patients. The majority of patients (136, 97.1%) who were Montelukast Sodium hospitalized were treated surgically. Wound debridement was the most common procedure performed in 91.2% of patients (Table 5). Table 5 Type of surgical procedures performed (N= 136) Type of surgical procedures Frequency Percentage Wound debridement 124 91.2 Treatment of fractures 89 65.4 Exploratory laparotomy 46 33.8 Craniotomy ± burr holes/Elevation of depressed skull fractures 30 22.1 Limb
amputation 28 20.6 Skin grafting/flaps 25 18.4 Pleural cavity drainage 12 8.8 Other surgical procedures 8 5.9 Outcome and follow up of patients A total of 98 complications were recorded in 72 (15.9%) patients the commonest being surgical site infections in accounting for 55.1% of patients (Table 6). The majority of patients (34, 63.0%) had polymicrobial bacterial profile. Staphylococcus aureus was the most common organism isolated accounting for 59.3% of all the bacterial isolates. According to multivariate regression logistic analysis, surgical site infections was significantly high in patients who presented late to the hospital (>24 hours) and those with open fractures (P < 0.001). Table 6 Distribution of patients according to treatment complications (N= 98) Treatment complications Frequency Percentage Surgical site infections 54 55.1 Complications of fractures 38 38.
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