2013 6) Subarea and July time period, and their interaction, wer

2013.6). Subarea and July time period, and their interaction, were considered as possible Alectinib molecular weight effects. One outlier was removed. Ripley’s L function is a second-order measure of spatial homogeneity, and summarizes the spatial dependence of sightings over a range of distances ( Besag, 1977, Nekola and Kraft, 2002 and Lancaster and Downes, 2004). This statistic can be used to examine whether the observed spatial pattern of sightings is clumped, evenly, or randomly

distributed. Using the Ripley’s L function, if a set of locations lack homogeneity, then the spatial distribution is considered clustered. The Ripley’s L function is stabilized in terms of the variance between dates (compared to the Ripley’s K function), and thus allows for comparisons between years. The

Ripley’s L function (Ls) is defined by: Ls=[λ−1n−1∑I(dijAngiogenesis inhibitor calculated, being the spatial equivalents to mean and standard deviation in classical statistics. The mean centre is the mean of the latitude and longitude of all the beluga sighting locations in a given

bay (subarea), thus providing the average geographic position for all sightings in Janus kinase (JAK) the time period in the whole subarea. Standard distance provides a measure of the degree to which the locations of beluga sightings were clustered or dispersed around the mean center. This measure is the standard deviation of the distance of each point from the mean centre. A large standard distance thus indicates a larger cluster of locations, and a small standard distance, vice-versa. The mean centers and standard distances for each subarea and survey were plotted and tabulated, to facilitate visual comparison of the extent of overlap among years. The KDE procedure takes a series of locations and then fits a probability density (usually a normal distribution) to each. Percent Volume Contours (PVCs) were created using ArcGIS (ESRI, 2004) Spatial Analyst Extension 9.3.1, and earlier using Hawth’s Analysis Tools v. 3.27. (The latter have since been incorporated into Geospatial Modelling Environment, http://www.spatialecology.com). KDEs were processed using a bivariate normal kernel estimator, and polygons derived from the KDE raster datasets (Sain et al., 1994, Seaman and Powell, 1996, Seaman et al., 1999 and Gitzen and Millspaugh, 2003).

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