Aspirin was used concurrently during 52% of the admissions, enoxaparin during 9%, and warfarin during 5%. The use of clopidogrel is increasing rapidly among children with cardiovascular diseases. This population has a high risk of bleeding, thrombosis, and mortality. SYN-117 chemical structure It therefore is imperative that future studies continue to evaluate the safety and efficacy of clopidogrel for these children.”
“Objective: To identify patient-specific self-assessment instruments, which measure physical function in patients with musculoskeletal disorders and to evaluate the descriptive properties and the psychometric qualities of these instruments.
Study Design and Setting: After a systematic
search, included instruments were evaluated psychometrically by the checklist “”quality criteria for
measurement properties of health status instruments.”"
Results: Twenty-three studies were included, referring to 12 instruments. Nine different versions of the Patient-Specific Functional Scale (PSFS) were identified. The practical elaboration of the different versions of the PSFS varied widely. None of the instruments were tested BYL719 molecular weight on all psychometric quality criteria of the checklist. The PSFS described by Cleland et al. was most extensively investigated and obtained exclusively positive scores. Overall, construct validity, reliability, and responsiveness were evaluated most frequently.
Conclusion: The descriptive properties and psychometric quality of patient-specific
instruments measuring physical function are only partly investigated. The PSFS was the most investigated instrument: nine different versions have been evaluated psychometrically. The version of Cleland et al. was most extensively investigated, obtained exclusively positive scores following the quality criteria by Terwee et al., and could be recommended for clinical use therefore. Future research will be necessary to confirm the psychometric quality of patient-specific instruments measuring physical function in patients with musculoskeletal disorders. (C) 2012 Elsevier Inc. All rights reserved.”
“Objective: It was to observe whether a microsurgical gross total removal (GTR) of a parasagittal meningioma (PSM) outside the sinus is a safe and efficient procedure. Method: We identify 58 parasagittal meningiomas patients. Medical charts, operative reports, imaging studies and Selleck Crenolanib clinical follow-up evaluations were reviewed. Results: GTR of the mass was achieved in 45 (77.7%) instances. The surgical mortality rate was 1.7%. The median follow-up time was 63 months. Conclusion: The surgical approach used in this group of patients afford that the great majority of tumors could be totally removed with low mortality, proving to be safe and effective.”
“Significant variability in weight loss and glycemic control has been observed in obese patients receiving bariatric surgery. Genetic factors may play a role in the different outcomes.
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