“Background: A helmet mandatory for people younger than 16


“Background: A helmet mandatory for people younger than 16 years was implemented in most Austrian provinces in the winter season 2009/2010. The objective of this study was to evaluate the impact of a ski helmet mandatory on age-dependent helmet use.

Methods: We compared helmet use in people aged 15 years or less and older than 15 years of Austrian provinces with and without helmet mandatory between the 2008/2009 (n = 16,342) and 2009/2010 (n = 32,011) winter seasons.

Results:

Helmet use in people aged 15 years or less in the 2009/2010 season increased by 16.2% in provinces with helmet mandatory and decreased by 2.1% in provinces AZD9291 Protein Tyrosine Kinase inhibitor without helmet mandatory (all p < 0.001), respectively. However, provinces with and without helmet mandatory did not differ regarding mean helmet use in people aged 15

years or less (92.2% vs. 92.8%, p = 0.506) in the 2009/2010 season. Helmet use in HDAC inhibitor review people older than 15 years in the 2009/2010 season had increased by 11.7% in provinces with helmet mandatory and by 17.9% in provinces without helmet mandatory (all p < 0.001), respectively. Helmet use in people older than 15 years was lower in provinces with helmet mandatory compared with provinces without mandatory (63.1% vs. 68.1%, p < 0.001) in the 2009/2010 season.

Conclusion: A helmet mandatory for people aged 15 years or less may increase helmet use in involved age groups when helmet use is relatively low. However, public discussions

and preventive helmet campaigns based on sound theories of health behavior change may also induce increases in helmet use in skiers aged older than 15 years without helmet mandatory.”
“Stemona selleck compound spp. have been traditionally used as natural pesticides and medicinal plants. S. curtisii, a dominant species of south and southwest Thailand, attracted attention for its insecticidal properties caused by specific alkaloids. A HPLC analytical method for quantitative determination of the major derivatives oxystemokerrine, stemocurtisine, stemocurtisinol, and stemofoline in root extracts of S. curtisii was developed. The method was validated for its linearity, precision, accuracy, limit of detection (LOD) and limit of quantitation (LOQ). Ten root samples were collected from various localities in Thailand and investigated for their insecticidal activities against neonate larvae of Spodoptera littoralis. Stemofoline was shown to possess the highest insecticidal activity with a LC50 value at 2.4 ppm and EC50 at 0.98 ppm. The present work provides a simultaneous HPLC analysis for quality assessment and standardization of S. curtisii raw materials, extracts and final products with regard to active Stemona alkaloids for further development as high quality natural insecticidal products. (C) 2012 Elsevier B.V. All rights reserved.

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