caviae, and iii) diverse subsets of strains that may be host adapted and/or “disease specialized”. The MLSA scheme developed herein in a large and diverse population of strains helped shed light on the unclear relationships among Aeromonas strains and aeromonosis. However, certain clades and the host- and/or disease-associated subsets of strains detected in this study included a limited number of strains. As a consequence,

additional studies are required to increase the size of the analyzed population and to confirm these results. Further work including a virulence analysis focusing on human VRT752271 mouse clinical clusters is also needed. Finally, the MLSA scheme proposed here appeared to be useful for taxonomic studies in the genus Aeromonas. Acknowledgments and funding We are particularly indebted to the microbiology YH25448 in vivo laboratory team of the Montpellier, France, academic hospital for providing some clinical isolates. This work was supported by the

Association des Biologistes de l’Ouest, by the Laboratoire de Diagnostic Bactériologique de l’Ecole Nationale Vétérinaire de Lyon and by ADEREMPHA (Association pour la Recherche et le Développement en Microbiologique & Pharmacie). We would like to thank all PX-478 in vitro members of the colBVH study group who participated in this study: F. Carmagnol (Cannes), E. Chachaty (Institut Gustave Roussy), C. Alba-Sauviat (Chaumont), C. Auvray (Charleville-Mézières), D. Barraud (Gonesse), Z. Benseddik (Chartres), A. Bertrou (Carcassone), F. Bessis (Cherbourg), H. Biessy (La Rochelle), V. Blanc (Antibes-Juan-les-pins), Y. Boucaud-Maitre (Lyon), P. Brunet & A. Michel (Marseille), B. Cancet (Villeneuve/Lot), J. Carrere (Hyères), A. Cecille (Digne-les-bains), G. Chambreuil (La Roche/Yon), P. Chantelat (Vesoul), H. Chardon (Aix-en-Provence), C. Charrel (Salon de Provence), H. De Montclos (Bourg-en-Bresse), J.W. Decousser (Dourdan; Rambouillet), J. M. Delarbre/A. Gravet (Mulhouse), D. Deligne (Remiremont), C. Denoix (La Réunion), J. Deregnaucourt (Paris (H. L. Bellon)), until F. Desroys du Roure (Chatellerault), S. Dubourdieu (Gisors), Z. El Harrif (Libourne), C. Eloy (Troyes), A. Evers (Annonay), C. Febvre (Montbéliard), D.

Fevre (Vienne), S. Gabriel (Monaco), M. J. Galanti (Coulommiers), E. Garnotel (Marseille (HIA Laveran)), M. Gavignet (Lavaur), F. Geffroy (Quimper), G. Grise (Elbeuf-Louviers), I. Gros (St Denis), I. Hermes (St-Malo), J. Heurte (Beauvais), E. Heusse (Bayeux), D. Jan (Laval), E. Jaouen (Sablé/Sarthe), S. Laluque (Montluçon), R. Lamarca (Narbonne), Laurens (Belfort), A. Le Coustumier (Cahors), E. Lecaillon (Perpignan), C. Lemble (Selestat), M. Leneveu (Poissy; St-Germain), S. Leotard (Grasse), M. N. Letouzey (Villefranche/saone), C. Malbrunot (Corbeil-Essonnes), O. Menouni (Montceau-les-Mines), M. Morel (Le Havre), C. Olive (Fort-de-France), B. Pangon (Versailles), J. G. Paul (Boulogne/mer), J. M. Perez (Pte-à-Pitre), P. Pouedras (Vannes), D. Pressac (Tulle), R.

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