[DOI: 10.1063/1.3120787]“
“This review considers why and how embryos are selected for transfer and with what consequences. It concludes that:

(i) current selection methods are inadequate or at least inadequately subjected to evidential scrutiny; (ii) decisions about number of embryos should be based not solely on input (numbers transferred) but on the likelihood of the transfer resulting in multiple pregnancies – out turn; and (iii) what is needed are better methods not just for selecting better embryos, but also for selecting responsible clinicians who collude less with their patients’ demands but advise them more responsibly. (C) 2013, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.”
“Thermally

induced phase transformation of buy GSK1210151A AS1842856 mouse Si-III/Si-XII zones formed by nanoindentation has been studied during low temperature (200 < T < 300 degrees C) thermal annealing by Raman microspectroscopy and transmission electron microscopy. Two sizes of spherical indenter tips have been used to create substantially different volumes of phase transformed zones in both crystalline (c-Si) and amorphous silicon (a-Si) to study the zone size and starting matrix effects. The overall transformation is from Si-III/XII to poly-or nanocrystalline Si-I through intermediate phases of Si-XIII and Si-IV. Attempts have been made to determine the exact transformation pathways. Two scenarios are possible: either Si-XII first MS-275 in vivo transforms to Si-III before transforming to Si-I through the intermediate phases or that Si-XII goes through the intermediate phases while Si-III transforms directly to Si-I. Finally, the phase transformations are slower in the larger indents and the starting matrix (crystalline or amorphous) has a substantial effect on the transformation kinetics of the small indents compared to the larger ones. We attribute this increased stability to both matrix effects (nucleation) and a difference in overall residual stress in indents made in a-Si compared to c-Si. (C) 2009 American Institute of Physics. [DOI: 10.1063/1.3124366]“
“Efforts

aimed at improving pregnancy rates have focused on the search for additional markers of viability to supplement current criteria for embryo selection. Time-lapse technology represents a powerful tool in assisted reproduction for evaluating embryos dynamically. Whilst standard methods of embryo assessment are based on subjective morphology evaluation at discrete time points, thereby limiting the information produced for embryo selection, time-lapse recording introduces several additional morphokinetic parameters for embryo evaluation. This additional information can improve implantation rates and reproductive outcomes. This review surveys available knowledge on time-lapse imaging to provide an overview of the advantages and applications of this technology. (C) 2013, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

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