In conclusion, this study has demonstrated

the genetic va

In conclusion, this study has demonstrated

the genetic variability of RVA during an extensive period of monitoring and the severity of these infections in pediatric patients. It has also emphasized the importance of ongoing laboratory surveillance to detect the emergence of new genotypes and to determine whether this is a consequence of the global program of immunization, and to assess its impact on pediatric health. Fundação Araucária/State of Paraná, Brazil. The authors declare no conflicts of interest. “
“Diarrheal diseases (DD) and acute respiratory infections (ARI) are a serious health this website problem in developing countries. They are the leading causes of morbidity and mortality in children younger than 5 years.1 and 2 Estimates published by the World Health Organization (WHO) in 2008 showed that respiratory infections affected 17% of children in this age group.3 Diarrheal diseases, in turn, are the cause of death of 2.5 million children/year.4 In Brazil, in 2009, respiratory infections killed 2,733 children younger than 5 years, which corresponds to 5.46% of deaths in this age group. The data also showed that ARI mortality (around 4.5% to 5.0%) was not click here much different

in proportion among the regions of the country, although it was higher in the North (7.51%) and Midwest (6.47%) Regions.5 Between 1998 and 2008, 33,363 deaths related to diarrhea Buspirone HCl were recorded in the country in individuals younger than five years; of these, 82% were younger than one year.6 These data differ according to region. While in the Southeast the number of episodes/child/year is 1.04, in the Northeast, it increases to 5.55.7 and 8 It has been observed that even after the advent of oral rehydration solution and

vaccination against rotavirus, both very effective methods to fight diarrheal diseases, their incidence still remains high.6, 9 and 10 With the goal of reducing infant mortality caused by DD, in 2001, the WHO analyzed 12 studies involving children aged 1 months to 5 years who had diarrhea to verify the effect of zinc on the disease. The results showed that this mineral supplementation was associated with a reduction in the duration of episodes of DD by 25% and decreased progression to persistent diarrhea. The studies also showed reduced incidence of diarrhea by two to three months after supplementation.11 Based on these results, since 2006, the WHO and the United Nations Children’s Fund (UNICEF) recommend zinc supplementation to treat and prevent future episodes of diarrhea,11 and 12 considering this is an essential micronutrient whose deficiency may increase the risk of infectious diseases.13 Zinc has also been shown to be effective in preventing infectious diseases of the respiratory tract.

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