Retrospective medical record review.
One of four Veterans Affairs multidisciplinary inpatient Polytrauma Rehabilitation Centers. One hundred twenty-eight Operation Enduring Freedom and Operation Iraqi Freedom military personnel with serious polytrauma injuries and concomitant pain categorized into three groups based on type of injuries: blast injuries, combat injuries other than blast, and noncombat, nonblast injuries.
Intensive, interdisciplinary inpatient rehabilitation and pain treatment.
Pain
intensity ratings; Functional GSK2118436 price Independence Measure scores; Rancho Los Amigos levels; and opioid analgesic doses.
Service members injured via blast demonstrated a broader spectrum of physical injuries, higher levels of admission and discharge opioid analgesic use, reduced improvement in pain intensity following treatment, and much higher rates of posttraumatic stress disorder and other psychiatric diagnoses than those injured via other means.
Blast injury may be associated with differential physical, emotional, and pain-related buy PF-6463922 symptoms that pose increased challenges for successful treatment.”
“Objectives: In vestibular schwannoma surgery postoperative facial nerve function is generally described as being related to tumor size, with 20 mm extrameatal diameter suggested as the threshold at which facial nerve function deteriorates. Near-total resection is accepted if the
risk to nerve function becomes unacceptably high. We sought to review outcomes of vestibular schwannoma resection Selleckchem BI2536 and follow residual tumor
fragments. Second, we pooled data to quantify the risk of regrowth and need for subsequent intervention.
Methods: Prospectively collected data on all patients undergoing microsurgical removal of vestibular schwannoma by the senior author over the past 15 years.
Results: Approximately 247 patients were identified, the spread of tumors was 74 intracanalicular, 120 15 mm or lesser, 57 between 16 and 30 mm, and 6 greater than 30 mm. Overall, 91.5% recovered to House-Brackmann Grade 1 or 2, with no difference between the groups with 15 mm or lesser and greater than 15 mm (p > 0.05); 26 had incomplete resection, and 3 showed regrowth. Pooled data: 193 near total resections with 12% regrowing; 181 subtotal resections with 30% regrowing. Of 108 growing fragments, 78% had intervention.
Conclusion: The present series suggests that the threshold for preservation of good facial nerve function may be moved to a tumor of 30-mm extrameatal diameter. Although historically tumor fragments were felt to have a low growth potential, the cumulative data would suggest that a significant proportion of fragments do grow and may need intervention.”
“Purpose: To investigate the protective effects of plumbagin against liver fibrosis and explore the influence of plumbagin on the proliferation of hepatic stellate cells (HSCs).
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